{"id":23338,"date":"2019-09-09T11:48:20","date_gmt":"2019-09-09T09:48:20","guid":{"rendered":"https:\/\/www.muscle-zone.pl\/blog\/?p=23338"},"modified":"2019-09-09T11:48:20","modified_gmt":"2019-09-09T09:48:20","slug":"jak-mozg-i-miesnie-reaguja-na-kreatyne-cz-2","status":"publish","type":"post","link":"https:\/\/www.muscle-zone.pl\/blog\/jak-mozg-i-miesnie-reaguja-na-kreatyne-cz-2\/","title":{"rendered":"Jak m\u00f3zg i mi\u0119\u015bnie reaguj\u0105 na kreatyn\u0119 cz.2"},"content":{"rendered":"<p><strong><a href=\"https:\/\/www.muscle-zone.pl\/blog\/jak-mozg-i-miesnie-reaguja-na-kreatyne-cz-1\/\">Poprzednia cz\u0119\u015b\u0107 artyku\u0142u<\/a> wskazywa\u0142a na podstawowe znaczenie biologiczne, genez\u0119 stosowania i przemiany biochemiczne kreatyny w organizmie cz\u0142owieka. Przyk\u0142adem bogatej funkcjonalno\u015bci tego zwi\u0105zku by\u0142o opisanie wp\u0142ywu jego niedobor\u00f3w na m\u00f3zg. Jakie jeszcze znaczenie ma suplementacja kreatyn\u0105 i czy jest korzystna tylko dla mi\u0119\u015bni?<\/strong><\/p>\n<h4><strong>Niedokrwienie i niedotlenienie <\/strong><\/h4>\n<p>Kiedy do m\u00f3zgu nie dociera wystarczaj\u0105ca ilo\u015b\u0107 krwi m\u00f3wimy o <strong>udarze niedokrwiennym<\/strong>. Udar niedokrwienny jest r\u00f3wnoznaczny z upo\u015bledzonym transportem tlenu do m\u00f3zgu. Druga posta\u0107 udaru dotyczy <strong>rozlewu krwi. <\/strong>Wylew mo\u017ce by\u0107 zlokalizowany\u00a0 bezpo\u015brednio w m\u00f3zgu lub w przestrzeniach znajduj\u0105cych si\u0119 z m\u00f3zgiem w bliskim po\u0142o\u017ceniu. Niedokrwienie wyst\u0119puje cz\u0119\u015bciej ni\u017c wylew i mo\u017ce by\u0107 wywo\u0142ane m.in. mia\u017cd\u017cyc\u0105, zawa\u0142em serca, zakrzepami, nieprawid\u0142ow\u0105 budow\u0105 serca lub migotaniem przedsionk\u00f3w.<\/p>\n<p>Okazuje si\u0119, \u017ce kreatyna mo\u017ce mie\u0107 zastosowanie w przypadku <strong>udaru niedokrwiennego<\/strong>, chocia\u017c raczej w formie profilaktyki ni\u017c leczenia. Wykazuje ona w\u0142a\u015bciwo\u015bci <a href=\"https:\/\/www.muscle-zone.pl\/sklep\/suplementy-na-koncentracje\"><strong>ochronne dla kom\u00f3rek nerwowych <\/strong><\/a>nawet w czasie wyst\u0105pienia udaru <sup>14,103,111 <\/sup>i mo\u017ce z powodzeniem <strong>ogranicza\u0107 wielko\u015b\u0107 szk\u00f3d<\/strong> wyst\u0119puj\u0105cych na skutek braku dop\u0142ywu krwi <sup>104<\/sup>. Suplementacja jednak powinna dotyczy\u0107 przede wszystkim okresu przed wyst\u0105pieniem udaru.<\/p>\n<p>Z drugiej strony niedob\u00f3r tlenu docieraj\u0105cego do m\u00f3zgu nie jest spotykany wy\u0142\u0105cznie podczas udaru niedokrwiennego. Zjawisko wyst\u0119puje w naturalnych okoliczno\u015bciach, np. podczas znacznych zmian ci\u015bnienia atmosferycznego i objawia si\u0119 m.in. <strong>zaburzeniami uwagi, koncentracji, mowy, zawrotami g\u0142owy, poczuciem spl\u0105tania.<\/strong> Takie sytuacje mog\u0105 dotyczy\u0107 os\u00f3b uprawiaj\u0105cych wspinaczk\u0119 wysokog\u00f3rsk\u0105 <sup>142,145<\/sup>.<\/p>\n<p>Istnieje badanie, w kt\u00f3rym sprawdzano czy w przypadku niedotlenienia ma zastosowanie suplementacja kreatyn\u0105. Wed\u0142ug nich spo\u017cywanie <a href=\"https:\/\/www.muscle-zone.pl\/sklep\/kreatyna\"><strong>20 gram\u00f3w kreatyny przez tydzie\u0144<\/strong><\/a> jest w stanie <strong>przygotowa\u0107 organizm na warunki niedoboru tlenowego,<\/strong> umo\u017cliwiaj\u0105c r\u00f3wnie\u017c znacznie lepsz\u0105 prac\u0119 m\u00f3zgu, ni\u017c w przypadku braku suplementacji<sup>94<\/sup><\/p>\n\n<h4><strong>Zanik mi\u0119\u015bni a suplementacja<\/strong><\/h4>\n<p>Skoro kreatyna jest \u015bwietnym suplementem dla os\u00f3b pragn\u0105cych budowa\u0107 mas\u0119 mi\u0119\u015bniow\u0105, to czy osoby nie trenuj\u0105ce zaobserwuj\u0105 jakie\u015b efekty jej stosowania?<\/p>\n<p>Wed\u0142ug danych suplementacja kreatyn\u0105 jest dobrym rozwi\u0105zaniem w przypadku <strong>utraty tkanki mi\u0119\u015bniowej<\/strong>, na przyk\u0142ad w wyniku przyjmowania statyn lub wyst\u0119powania chor\u00f3b genetycznych.<\/p>\n<p>Statyny s\u0105 podawane w du\u017cych dawkach osobom<a href=\"https:\/\/www.muscle-zone.pl\/blog\/prewencja-chorob-sercowo-naczyniowych-co-nowego-w-2019\/\"> z chorobami sercowo-naczyniowymi<\/a> w celu <strong>zbicia cholesterolu<\/strong> we krwi i poprawy jego frakcji. S\u0105 to substancje <strong>tanie,<\/strong> w du\u017cej mierze <strong>bezpieczne i skuteczne<\/strong>, w przeciwie\u0144stwie do innych preparat\u00f3w maj\u0105cych wykazywa\u0107 korzystne w\u0142a\u015bciwo\u015bci w leczeniu zaburze\u0144 lipidowych we krwi <sup>70-75<\/sup>.<\/p>\n<p>Niestety d\u0142ugotrwa\u0142a <strong>terapia statynami<\/strong> mo\u017ce uszkadza\u0107 mi\u0119\u015bnie (miopatia statynowa), powoduj\u0105c<strong> b\u00f3l, skurcze,<\/strong> a nawet zwi\u0119ksza\u0107 ryzyko <strong>zgonu<\/strong> u os\u00f3b po przebytym zawale lub z chorob\u0105 niedokrwienn\u0105 serca <sup>58 - 62,65,66<\/sup>. <strong>Suplementacja kreatyny zapobiega uszkodzeniom mi\u0119\u015bni<\/strong> zwi\u0105zanym z przyjmowaniem statyn <sup>63,64<\/sup>, a co ciekawe, jej endogenna synteza to ryzyko zwi\u0119ksza <sup>67- 69<\/sup>.<\/p>\n<p>Podawanie kreatyny znajduje swoje zastosowanie r\u00f3wnie\u017c w\u015br\u00f3d <strong>os\u00f3b starszych<\/strong>. W wyniku starzenia dochodzi do degradacji struktur mi\u0119\u015bniowych, co zmniejsza <strong>si\u0142\u0119 i mas\u0119 mi\u0119\u015bni<\/strong>, utrudnia codzienne funkcjonowanie, zwi\u0119ksza ryzyko niebezpiecznych <strong>upadk\u00f3w,<\/strong><a href=\"https:\/\/www.muscle-zone.pl\/sklep\/zdrowie\"> wp\u0142ywa na <strong>pogorszenie nastroju<\/strong> <\/a><sup>76,77<\/sup>. Suplementowanie kreatyny pomaga w utrzymaniu sprawno\u015bci fizycznej przez osoby starsze, za pomoc\u0105 wy\u017cej opisanych mechanizm\u00f3w<sup>78-83<\/sup>. Ponadto w\u0142a\u015bciwa suplementacja pomaga leczy\u0107 <strong>dystrofie mi\u0119\u015bniowe<\/strong> <sup>84-92<\/sup>.<\/p>\n<h4><strong>Unikanie mi\u0119sa<\/strong><\/h4>\n<p>Chocia\u017c diety ro\u015blinne maj\u0105 wiele dobrych cech, takich jak np. ogromny potencja\u0142 antyoksydacyjny, to s\u0105 <strong>ubogie w kreatyn\u0119<\/strong>. \u0179r\u00f3d\u0142em aminokwasu s\u0105 wy\u0142\u0105cznie produkty pochodzenia <strong>zwierz\u0119cego<\/strong>, zw\u0142aszcza ich tkanka mi\u0119\u015bniowa <sup>6-9<\/sup>.<\/p>\n<p>W przypadku os\u00f3b spo\u017cywaj\u0105cych<strong> mleko, jaja, sery i nabia\u0142<\/strong>, problem nie jest tak widoczny jak u <strong>\u015bcis\u0142ych wegan<\/strong>, ale pog\u0142\u0119bia si\u0119 podczas wzmo\u017conej pracy <strong>fizycznej lub umys\u0142owej<\/strong> <sup>57<\/sup>.<\/p>\n<p>W wyniku niedobor\u00f3w kreatyny organizm wzmaga syntez\u0119 endogenn\u0105, co z kolei prowadzi do <strong>stresu metabolicznego<\/strong>. Pomimo tych proces\u00f3w ilo\u015b\u0107 kreatyny wci\u0105\u017c jest <strong>zbyt niska w mi\u0119\u015bniach i krwi<\/strong> os\u00f3b na dietach ro\u015blinnych <sup>41-45<\/sup>.<\/p>\n<p>Prawdopodobnie organizm stosuje mechanizm <strong>oszcz\u0119dzania kreatyny<\/strong> na rzecz m\u00f3zgu. Co ciekawe zauwa\u017cono, \u017ce w wyniku jej niedobor\u00f3w, poziomy w m\u00f3zgu nie podlegaj\u0105 patologicznym zmianom <sup>46<\/sup>.<\/p>\n<p>Poza tym weganie i wegetarianie dostarczaj\u0105 <a href=\"https:\/\/www.muscle-zone.pl\/index.php?route=product%2Fsearch&amp;filter_name=b12\">niewiele witaminy <strong>B12<\/strong>,<\/a> prowadz\u0105c do powstawania niedobor\u00f3w pokarmowych, a w konsekwencji <strong>pog\u0142\u0119bienia niedoboru kreatyny<\/strong> <sup>47-49<\/sup>.<\/p>\n<p>O zwi\u0119kszonym zapotrzebowaniu na kreatyn\u0119 przez osoby na dietach ro\u015blinnych \u015bwiadczy fakt, \u017ce podawanie jej wi\u0105\u017ce si\u0119 z <strong>szybsz\u0105 odbudow\u0105<\/strong> tego zwi\u0105zku w ich mi\u0119\u015bniach, <strong>wi\u0119kszym efektem<\/strong> ergogenicznym i <strong>wzrostem wydolno\u015bci<\/strong> umys\u0142owej, ni\u017c u os\u00f3b jedz\u0105cych produkty zwierz\u0119ce. Weganie i wegetarianie powinni przyjmowa\u0107 oko\u0142o <strong>1 gram kreatyny<\/strong> dziennie <sup>42-57<\/sup> .<\/p>\n<h4><strong>Nie tylko dla sportowc\u00f3w<\/strong><\/h4>\n<p>Chocia\u017c przyjmowanie kreatyny przynosi korzy\u015b\u0107 dla mi\u0119\u015bni podczas ich intensywnej pracy, to pozosta\u0142e jej funkcje mog\u0105 by\u0107 wykorzystywane do co najmniej kilkunastu innych cel\u00f3w.<\/p>\n<p>Wzrost st\u0119\u017cenia fosfokreatyny w ustroju wywiera efekt terapeutyczny w\u015br\u00f3d os\u00f3b choruj\u0105cych na <strong>zaniki mi\u0119\u015bni<\/strong>, obci\u0105\u017conych ryzykiem <strong>miopatii<\/strong> statynowej, choruj\u0105cych na zaburzenia<strong> psychiczne<\/strong> lub b\u0119d\u0105cych w grupie ryzyka <strong>udaru niedokrwiennego m\u00f3zgu<\/strong>.<\/p>\n<p>Kreatyna powinna stanowi\u0107 profilaktyczne uzupe\u0142nienie diety dla os\u00f3b <strong>unikaj\u0105cych spo\u017cywania <\/strong>produkt\u00f3w pochodzenia zwierz\u0119cego, os\u00f3b <strong>starszych,<\/strong> <strong>alpinist\u00f3w,<\/strong> os\u00f3b wykonuj\u0105cych zawodowo <strong>ci\u0119\u017ck\u0105 prac\u0119<\/strong> fizyczn\u0105 lub umys\u0142ow\u0105, a tak\u017ce <a href=\"https:\/\/www.muscle-zone.pl\/blog\/a-trzeba-bylo-spac-czyli-dlaczego-sen-jest-tak-wazny\/\">cierpi\u0105cych na <strong>zaburzenia snu<\/strong><\/a>.<\/p>\n<p>Przyjmowanie suplement\u00f3w kreatyny zosta\u0142o uznane za bezpieczne, nawet w dawce <strong>20 gram\u00f3w na dob\u0119<\/strong>. Nie dotyczy to jednak os\u00f3b choruj\u0105cych na <strong>niewydolno\u015b\u0107 nerek<\/strong>, u kt\u00f3rych suplementacja zwi\u0119ksza ryzyko uszkodze\u0144 i powik\u0142a\u0144 <sup>51,146-48<\/sup>.<\/p>\n<style>details{\r\n  background-color: white;\r\n  padding: 5px 10px;\r\n  box-shadow: 0 4px 8px 0 rgba(55,92,192,.08),0 0 1px 0 rgba(18,32,73,.08);\r\n}\r\nsummary{\r\n  display: list-item;\r\n  font-weight: bold;\r\n  font-size: 18px;\r\n}\r\nsummary:hover{\r\n  cursor: pointer;\r\n}<\/style><details><summary>Bibliografia <\/summary>\n<ol>\n<li>Wallimann T, Tokarska\u2010Schlattner M, Schlattner U. The creatine kinase system and pleiotropic effects of creatine. Amino Acids. 2011;40(5):1271\u20101296.<\/li>\n<li>Sahlin K, Harris RC. The creatine kinase reaction: a simple reaction with functional complexity. Amino Acids. 2011;40(5):1363\u20101367.<\/li>\n<li>Wyss M, Kaddurah\u2010Daouk R. Creatine and creatinine metabolism. 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J Am Soc Nephrol. 1996;7(1):118\u2010127.\u00a0<\/details><\/li>\n<\/ol>\n","protected":false},"excerpt":{"rendered":"<p>Poprzednia cz\u0119\u015b\u0107 artyku\u0142u wskazywa\u0142a na podstawowe znaczenie biologiczne, genez\u0119 stosowania i przemiany biochemiczne kreatyny w organizmie cz\u0142owieka. Przyk\u0142adem bogatej funkcjonalno\u015bci&#8230;<\/p>\n","protected":false},"author":101,"featured_media":23341,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[121,1312,51],"tags":[],"class_list":["post-23338","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-healthy-lifestyle","category-kij-w-mrowisko","category-suplementacja"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v23.1 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Jak m\u00f3zg i mi\u0119\u015bnie reaguj\u0105 na kreatyn\u0119 cz.2<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.muscle-zone.pl\/blog\/jak-mozg-i-miesnie-reaguja-na-kreatyne-cz-2\/\" \/>\n<meta property=\"og:locale\" content=\"pl_PL\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Jak m\u00f3zg i mi\u0119\u015bnie reaguj\u0105 na kreatyn\u0119 cz.2\" \/>\n<meta property=\"og:description\" content=\"Poprzednia cz\u0119\u015b\u0107 artyku\u0142u wskazywa\u0142a na podstawowe znaczenie biologiczne, genez\u0119 stosowania i przemiany biochemiczne kreatyny w organizmie cz\u0142owieka. 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